Gastroesophageal reflux disease, or acid reflux, escapes into the esophagus of the stomach. This retreating fluid can damage food borrowing in some of the patients. There is an enzyme called pepsin which is used to digest the stomach acid and protein in the retreating fluid. The most harmful substance in this liquid is the most harmful substance. Reflux is a chronic condition that usually lasts for life once it starts. The damage caused by the reflux (esophagitis) is also a chronic condition.
When the treatment is started, even if the food intake is improved, the treatment is restored after a few months. Although reflux can also occur in normal people, this reflux lasts longer in patients. People have mechanisms to protect themselves from this acid reflux. Most of the reflux comes into play when it is standing and it returns to the midst with the effect of gravity. And while people are swallowing, this fluid is going back to the pond.
In addition, there are bicarbonate in saliva. Bicarbonate is basic and acid neutralizes the effects of esophagus. The effectiveness of these three protective mechanisms is greatly reduced when you are sleeping at night. Swallowing stops, saliva and gravity are reduced. As a result, the acid will stay longer in the nighttime cul-de-sac and cause more damage. Some cases lead to more reflux in humans.
Pregnancy is one of them. Due to rising pregnancy hormone levels, the sphincter pressure at the lower end of the food tube is reduced. There is also an increase in the pressure of the abdomen due to the growing fetus. Reflux is increasing due to these two effects. In addition, some diseases that weaken food borne muscles, such as scleroderma or mixed connective tissue diseases, can cause reflux.